Boston (44-20-5) will travel to Detroit (26-34-9) on the tail end of a back-to-back situation that saw the club top the Columbus Blue Jackets in overtime by a 3-2 score on Monday.
The Bruins will try to push their current win streak to three games without their top scorer David Pastrnak and third liner Trent Frederic, both men being ruled out after sustaining upper-body injuries last night.
All signs point to forward Curtis Lazar as well as defensemen Josh Brown and Connor Clifton being healthy scratched against the Wings.
Between the pipes, the B's will turn to rookie sensation Jeremy Swayman (20-9-3), who'll most likely get to face off against Detroit's Alex Nedeljkovic (17-21-8) down the other end.
Unless the Bruins decide to make last-minute changes between the warm-up period and the initial puck drop, here are the expected lines for tonight's game:
Brad Marchand � Patrice Bergeron � Jake Debrusk
Taylor Hall � Erik Haula � Tomas Nosek
Nick Foligno � Charlie Coyle � Craig Smith
Anton Blidh � Jack Studnicka � Marc McLaughlin
Hampus Lindholm � Charlie McAvoy
Matthew Grzelcyk � Brandon Carlo
Derek Forbort � Mike Reilly
Jeremy Swayman
Linus Ullmark
The opening face-off between the Bruins and Red Wings is scheduled for 7:30pm ET at Detroit's Little Caesars Arena.